张焜

作者: 时间:2019-07-10 点击数:

张焜

ZHANGKUN

教授

所属学院:

生物医药学院

导师类别:

博士生导师、硕士生导师

职 务:

广东工业大学天然药物与绿色化学研究所所长

科研方向:

天然药物化学,有机合成化学

联系方式:

博士招生学院:

生物医药学院

硕士招生学院:

生物医药学院



个人简述

(限300字)

张焜,男,广东罗定人,博士,教授,博士生导师,硕士生导师。现任五邑大学党委书记,广东工业大学天然药物与绿色化学研究所所长,Allan H. Conney抗肿瘤药物研究所所长。近年在《J Am Chem Soc》、《Chem Comm》、《Chem-Eur J》、《Org Biomol Chem》、《Tetrahedron Lett》等国内外杂志发表论文80多篇,三大收录40余篇。申请发明专利55项。主持国家基金1项,省部级项目7项,其它项目4项。。



学科领域

科学学位

应用化学化学工艺食品科学化学工程与技术

专业学位

化学工程



教育背景

1997年毕业于兰州大学获得理学博士学位

1990年毕业于广东工学院获得硕士学位

1985年毕业于广东工学院获得学士学位



工作经历

1999/12 – 至今,广东工业大学,轻工化工学院,教授

1999年,美国圣路易士大学访问学者,从事抗癌中药开发研究

1995/12 – 1999/12,广东工业大学,轻工化工学院,副教授

1992/12 – 1995/12,广东工业大学,轻工化工学院,讲师

1985/7 – 1987/8,广东工业大学,轻工化工学院,任教



主要荣誉

2006年获得广东省科学厅科技进步奖二等奖

2007年获得广东省科学厅科技进步奖三等奖

2001、2010年分别获得广东省教学成果一等奖



主要论文

1. Huang Huarong, He Yan, Xiao-Xing Cui, Susan Goodin, Hong Wang, Zhiyun Du, Donli Li, Kun Zhang, Ah-Ng Kong, Robert S DiPaola, Chung S Yang, Allan H. Conney, Xi Zheng. Potent inhibitory effect of δ-tocopherol on prostate cancer cells cultured in vitro and grown as xenograft tumors in vivo. J Agric Food Chem, 2014; 62: 10752-8 (SCI,一区)

2. Shijing Ma, Yan He*, Bowen Wang, Sen Jiang, Xi Zheng, Yue liu, Zhang Kun , Zhiyun Du. Dimocarpus longan Lour. peel extracts mediated biosynthesis of silver nanoparticles: Synthesis, characterization, antibacterial activities and cytotoxic effects on Prostate cancer PC-3 cells. Int J Nanomedicine , 2014 (SCI,二区)

3. Wenjun Li, QianfaJia, Zhiyun Du,Kun Zhang andJian Wang*. Amine-Catalyzed Enantioselective 1,3-Dipolar Cycloadditions of Aldehydes to C,N-Cyclic Azomethine Imines. Chem. Eur. J. 2014, 20, 4559 (SCI 二区,IF= 5.696)

4. Wenjun Li, Jia Wei, QianfaJia, Zhiyun Du,* Kun Zhang, and Jian Wang*.Asymmetric Synthesis of Tetrahydroquinolines through a[3+2] Cycloaddition Controlled by Dienamine Catalysis.Chem. Eur. J.2014, 20, 6592.

5. Wenjun Li, Zhiyun Du,*Jiayao Huang, Qianfa Jia, Kun Zhang and Jian Wang*.Direct access to 1,2,3-triazoles throughorganocatalytic 1,3-dipolar cycloaddition reactionof allyl ketones with azides.Green Chem., 2014, 16, 3003. (SCI 二区, IF = 6.828)

6. Fu H. L.; Chang H.; Shen J.; Yu L.; Qin B. *; Zhang K. *; Zeng H. Q. *, An unusual macrocyclization reagent for highly selective one-pot synthesis of strained macrocyclic aromatic hexamers. Chemical Communications 2014, 50 (27), 3582-3584.

7. QianfaJia, Pooi Ming ShurnBenjamin,JiayaoHuang,Zhiyun Du*,Xi Zheng,KunZhang,AllanH.Conney,Jian Wang*. Synthesis of 3,4-Disubsituted Isoxazoles via Enamine [3+2] Cycloaddition. SYNLETT .2013, 24, 79 (SCI 三区,IF=2.463)

8. Pan-pan Wu; Ping He; Su-qing Zhao*; Tian-ming Huang; Yu-jing Lu; Kun Zhang*. Effects of ursolic acid derivatives on Caco-2 cells and their alleviating role in streptozocin-induced diabetic rats [J]. Molecules, 2014, 19(8): 12559-12576. (SCI三区,IF=2.095)

9. Dai-Ying Zhou, Kun Zhang, Allan H. Conney, Ning Ding, Xiao-Xing Cui, Hui Wang, Michael Verano, Su-qing Zhao, Yan-Xiong Fang, Xi Zheng, Zhi-Yun Du, Synthesis and evaluation of curcumin-related compounds containing benzyl piperidone for their effects on human cancer cells, Chem. Pharm.Bull., 61(11), 1-7, 2013

10. Zhi-Yun Du, Xingchuan Wei, Mou-Tuan Huang, Xi Zheng, Yue Liu, Allan H. Conney and Kun Zhang*. Anti-proliferative, Anti-inflammatory and Antioxidant Effects of Curcumin Analogue A2. Arch Pharm. Res., 2013,

11. HaoliangFu, Ying Liu, Huaqiang Zeng, Kun Zhang. Shape-persistent H-bonded macrocyclic aromatic pentamers. Chem Comm, 2013, 49, 4127.

12. Yongfu Jiang, Zhiyun Du, Guihua Xue , Qian Chen, Yujing Lu, Xi Zheng, Allan H. Conney, Kun Zhang. Synthesis and Biological Evaluation of Unsymmetrical Curcumin Analogues as Tyrosinase Inhibitors. Molecules, 2013, 18, 3948-3961.

13. He Y, Du Z*, Lv H, QianfaJia,Zhikai Tang, Xi Zheng, Kun Zhang, Fenghua Zhao. Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel. International journal of nanomedicine, 2013, 8,1809

14. Jiang Y. F.; Du Z. Y. *; Xue G. H.; Chen Q.; Lu Y. J.; Zheng X.; Conney A. H.; Zhang K. *, Synthesis and Biological Evaluation of Unsymmetrical Curcumin Analogues as Tyrosinase Inhibitors. Molecules 2013, 18 (4), 3948-3961.



地址:广州市番禺区广州大学城外环西路100号广东工业大学行政楼325    邮编:510006

电话:020-39322722    邮箱:yzb@gdut.edu.cn