教育背景  

2004/09 – 2007/07，华南理工大学，计算机应用技术，博士。

2001/09 – 2004/07，华南师范大学，应用数学，硕士。

1997/09 – 2001/07，华南师范大学，基础数学，学士。

工作经历  

2007/07 – 现在，广东工业大学，计算机学院，副教授。

发表论文  

[1]Guosheng Gu, Haojie Han, Haowei Wu, Yuping Sun, Ping Liu, Guihua Jiang, Jiehang Deng, Guobo Xie, Jiazhou Chen, H³CDR : An Anti-cancer Drug Response Prediction Model Driven by Heterogeneous and Homogeneous Hybrid Graph Neural Network. IEEE Transactions on Computational Biology and Bioinformatics. 2026, 23(1): 284-296. (CCF B)

[2]Guosheng Gu, Haowei Wu, Haojie Han, Zhiyi Lin, Yuping Sun, Guobo Xie, Qing Su, Zhenguo Liu. MVSGDR: multi-view stacked graph convolutional network for drug repositioning. Briefings in Bioinformatics, 2025, 26(5), bbaf396. (CCF B)

[3]Jiehang Deng, Jianfa Yang, Guosheng Gu*(通讯作者), Chao Liu, Xiaodong Kang, Dongyun Zheng, He Shi, Jian Zhao. DiaDet-R: A lightweight and accurate rotated detector for diatom detection in drowning diagnostics. Expert Systems with Applications, 2025, 265: 125958. (SCI一区)

[4]Guobo Xie, Weijun Li, Guosheng Gu*(通讯作者), Zhiyi Lin, and Dayin Li. A miRNA-Disease Association Prediction Method Integrating Graph Matrix Factorization With L₂₁ Similarity Constraint and Network Projection Fusion. IEEE Transactions on Computational Biology and Bioinformatics, 2025, 22(2): 591-602. (CCF B)

[5]GuoBo Xie, HaoJie Xu, Guosheng Gu*(通讯作者), ZhiYi Lin, JunRui Yu and RuiBin Chen . MLWNNR: LncRNA-Disease Association Prediction with Multi-Kernel Learning-Driven Weighted Nuclear Norm Regularization. Interdiscip Sci Comput Life Sci (2025): 1-18. (SCI二区)

[6]Jiehang Deng, Jianfa Yang, Haomin Wei, Guosheng Gu*(通讯作者), Qingqing Xiang, Yukun Du, Chao Liu, Zhiqiang Chen, Lunke Fei, Jian Zhao.A high-efficiency local and global detector for diatom-based drowning diagnosis.Engineering Applications of Artificial Intelligence, 2024, 138: 109296. (SCI一区)

[7]GuoBo Xie, RuiBin Chen, ZhiYi Lin*, Guosheng Gu*(通讯作者), JunRui Yu, Zhenguo Liu, Ji Cui, Lieqing Lin, Langcheng Chen. Predicting lncRNA–disease associations based on combining selective similarity matrix fusion and bidirectional linear neighborhood label propagation. Briefings in Bioinformatics, 2023, 24(1): bbac595.(CCF B)

[8]Guosheng Gu, Shaowei Gan, Jiehang Deng*, et al. Automated diatom detection in forensic drowning diagnosis using a single shot multibox detector with plump receptive field. Applied Soft Computing, 2022:108885.(SCI二区)

[9]Guosheng Gu, Huihong Lu, Jiehang Deng*, et al. A synergetic image encryption method based on discrete fractional random transform and chaotic maps. Multimedia Tools and Applications, 2023, 82(14): 22123-22147.

[10]Jiehang Deng, Zihang Hu, Jinwen He, Jiaxin Liu, Guoqing Qiao, Guosheng Gu*(通讯作者), Shaowei Weng. Irregular feature enhancer for low-dose CT denoising. Multimedia Systems. 2024, 30: 359.

[11]Guobo Xie, Weijie Xie, Guosheng Guosheng Gu*(通讯作者), et al. A vector projection similarity-based method for miRNA-disease association prediction. Analytical Biochemistry, 2024, 687: 115431.

[12]Guobo Xie, Shigang Liu, Guosheng Gu*(通讯作者), Zhiyi Lin, Junrui Yu, Ruibin Chen, Weijie Xie, Haojie Xu. LUNCRW: Prediction of potential lncRNA-disease associations based on unbalanced neighborhood constraint random walk. Analytical Biochemistry. 2023, 679:115297.

[13]Jiehang Deng, Weiming Wang, Guosheng Gu*(通讯作者), et al. Wildfire susceptibility prediction using a multisource and spatiotemporal cooperative approach. Earth Science Informatics, 2023, 16(4): 3511-3529.

[14]Jiehang Deng, Haomin Wei, Zhenxiang Lai, Guosheng Gu*(通讯作者), Zhiqiang Chen, Leo Chen, Lei Ding. Spatial Transform Depthwise Over-Parameterized Convolution Recurrent Neural Network for License Plate Recognition in Complex Environment. Journal of Computing and Information Science in Engineering, 2023, 23(1): 010201.

[15]Jiehan Deng, Haomin Chen, Zhongming Yuan, Guosheng Gu*(通讯作者), Shihe Xu, Shaowei Weng, Hao Wang. An enhanced image quality assessment by synergizing superpixels and visual saliency. Journal of Visual Communication and Image Representation, 2022, 88: 103610.

[16]Jiehang Deng, Wenquan Guo, Youwei Zhao, Jingjian Liu, Runhao Lai, Guosheng Gu*(通讯作者), et al. Identification of diatom taxonomy by a combination of region-based full convolutional network, online hard example mining, and shape priors of diatoms. International Journal of Legal Medicine, 2021, 135: 1-12.

[17] Jiehang Deng, Haomin Wei, Dongdong He, Guosheng Gu*(通讯作者), et al. A coarse to fine framework for recognizing and locating multiple diatoms with highly complex backgrounds in forensic investigation. Multimedia Tools and Applications, 2021, 81: 4839-4857.

[18]Guobo Xie, Jianming Li, Guosheng Gu*(通讯作者), et al. BGMSDDA: a bipartite graph diffusion algorithm with multiple similarity integration for drug-disease association prediction. MOLECULAR OMICS, 2021, 17(6): 997-1011.

[19]Guobo Xie, Haojie Xu, Jianming Li, Guosheng Gu*(通讯作者), et al. DRPADC: A novel drug repositioning algorithm predicting adaptive drugs for COVID-19. Computers & Chemical Engineering, 2022, 166: 107947. (SCI二区)

[20]Guobo Xie, Changhai Wu, Guosheng Gu*(通讯作者), et al. HAUBRW: Hybrid algorithm and unbalanced bi-random walk for predicting lncRNA-disease associations. Genomics, 2020, 112(6): 4777-4787. (SCI二区)

[21]Jiehang Deng, Jixiang Yang, Shaowei Weng, Guosheng Gu*(通讯作者), Zheng Li. Copy-move Forgery Detection Robust to Various Transformation and Degradation Attacks. KSII Transactions on Internet and Information Systems, 2018, 12(9): 4467-4486.

[22]Guosheng Gu, Jie Ling, Guobo Xie, Zheng Li. A chaotic-cipher-based packet body encryption algorithm for JPEG2000 images. Signal Processing: Image Communication, 2016, 40: 52-64.

[23]Guosheng Gu, Jie Ling. A fast image encryption method by using chaotic 3D cat maps, Optik - International Journal for Light and Electron Optics, 2014, 125(17): 4700-4705.

[24]邓杰航;王晓宇;赵建;刘超;康晓东;顾国生*(通讯作者). 复杂背景下高分辨率电镜的小环藻识别. 计算机工程与设计, 2019(1): 167-172.

[25]邓杰航, 毋鹏杰, 余汉君, 林小平, 张静, 顾国生*(通讯作者). 基于扩展梯度算子的结构相似度图像质量评价方法. 科学技术与工程, 2018(27): 42-47.

[26]柳毅, 顾国生*(通讯作者). 一种新的轻量级RFID双向认证协议. 计算机科学, 2017(02): 213-215+234.

[27]邓杰航, 袁仲鸣, 林好润, 顾国生*(通讯作者). 协同超像素和视觉显著性的图像质量评价. 广东工业大学学报, 2021, 38(05): 33-39.

[28]顾国生，邓杰航，苏庆. “两型四项五融合”的信息安全专业人才实践能力培养. 计算机教育, 2022, 4: 188-193.

主持项目

[1]广东省科技计划项目：警用动态多维采集综合分析系统关键技术研究与应用

[2]广东省科技计划项目：多级别分层次智能网络视频监控系统关键技术研究及产业化

[3]广东省科技计划项目：基于物联网的远程无线急危重症会诊救治系统

[4]广州市科技创新发展专项资金项目：基于云计算的警务视频布控分析系统关键技术研究与应用

[5]广州市科协产学研促进经费项目：基于私有云存储和压缩感知编码技术的视频监控系统

[6]南沙区科技计划项目：面向复杂场景的新一代智能设备数字化售后服务平台

[7]北京空间飞行器总体设计部项目：光学卫星数据处理技术

[8]中国人民解放军军事科学院项目：智能规划终端样本试制及测试

[9]教育部产学研协同育人项目：面向新工科人才培养改革的信息安全专业课程体系建设

[10]广东省核心软件攻关工程工业软件人才培养项目：基于核心软件攻关工程工业软件产品的《数据库系统》标杆性课程建设

授权发明专利

[1]一种基于异同构多分支的抗癌药物反应预测方法. ZL202510075959.X（已授权）

[2]一种基于MSLQA-Net的轻量化脑肿瘤分割方法. ZL202510033486.7（已授权）

[3]一种融合三种注意力的肝肿瘤分割方法. ZL202510089749.6（已授权）

[4]一种基于高效特征提取与融合的溺死硅藻检测方法. ZL 202510089535.9（已授权）

[5]一种基于空域和频域的轻量化图像超分辨率方法和装置. ZL202510130560.7（已授权）

[6]一种基于多向空间特征的肝肿瘤分割方法. ZL202510122987.2（已授权）

[7]一种基于紧框架小波残差扩散模型的低剂量CT去噪方法. ZL202510123213.1（已授权）

[8]基于改进YOLOX的道路井盖状态检测方法. ZL202311274299.5（已授权）

[9]一种基于CrossMAE的脑胶质瘤分割方法. ZL202411911728.X（已授权）

[10]一种基于目标一致多分辨融合的肺结节分割方法和装置. ZL202411910756.X（已授权）

[11]一种基于ABVM-UNet的肺结节分割方法及装置. ZL202411912335.0（已授权）

[12]一种基于多区域感知注意力的脑肿瘤分割方法. ZL202411982971.0（已授权）

[13]一种基于GTF卷积及多频双注意力的肝肿瘤分割方法. ZL202411925420.0（已授权）

[14]一种基于多视图堆叠跳级图卷积网络的药物重定位方法. ZL202411989199.5（已授权）

[15]基于加权核规范正则化算法的lncRNA-疾病关联预测方法. ZL20231 0121308.0（已授权）

[16]药物-疾病关联预测方法及系统. ZL202110407996.8（已授权）

[17]基于混沌映射和选择性Signcryption的DICOM图像非对称加密方法. ZL202110088780.X（已授权）

[18]多图像加密方法及解密方法. ZL202110351406.4（已授权）

[19]一种融合显著性和超像素的电镜硅藻图像分割方法及装置. ZL201910754900.8（已授权）

[20]基于离散分数变换和混沌函数的图像加密方法及装置. ZL201910689725.9（已授权）

[21]文本图像的处理方法及装置. ZL201910795552.9（已授权）

[22]一种对提取的硅藻区域进行硅藻类型识别方法及装置. ZL201810414537.0（已授权）

[23]一种小环藻识别方法及装置. ZL201710977279.2（已授权）

教学活动

数据库系统、算法设计与分析、应用概率统计