主要论文
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1.Wang, X.; Piro, B.; Reisberg, S.; Anquetin, G.; De Rocquigny, H.; Jiang, P.; Wang, Q.; Wu,, W.; Pham, M.-C.; Dong, C.-Z.*(2014) “Direct, Reagentless Electrochemical Detection of the BIR3 Domain of X-linked Inhibitor of Apoptosis Protein Using a Peptide-based Conducting Polymer Sensor”, Biosens Bioelectron, 61, 57-62.
2.Wang, X.; Reisberg, S.; Serradji, N.; Anquetin, G.; Pham, M.-C.; Wu, W.; Dong, C.-Z.; Piro, B. (2014) “E-assay concept: Detection of bisphenol A with a label-free electrochemical competitive immunoassay”, Biosens Bioelectron, 53, 214-219.
3.He, Y.-W.; Dong, C.-Z.; Zhao, J-Y; Ma, L.-L. ; Li, Y.-H.; Aisa H. A. (2014), “1, 2, 3-Triazole-containing derivatives of rupestonic acid: Click-chemical synthesis and antiviral activities against influenza viruses”, Eur. J. Med. Chem., 76, 245-55.
4.Shi J., Chen J., Serradji N., Xu X., Zhou H., Ma Y., Sun Z., Jiang P., Du Y., Yang J;, Dong C.-Z., Wang Q. (2013), “PMS1077 Sensitizes TNF-α Induced Apoptosis in Human Prostate Cancer Cells by Blocking NF-κB Signaling Pathway”, PLoS One., 8, e61132.
5.Dong, C.-Z.; Tian S, Choi WT, Kumar S, Liu D, Xu Y, Han X, Huang Z, An J. (2012) “Critical Role in CXCR4 Signaling and Internalization of the Polypeptide Main Chain in the Amino Terminus of SDF-1α Probed by Novel N-Methylated Synthetically and Modularly Modified Chemokine Analogues”, Biochemistry, 51, 5951-7.
6.N Griffete, H. Li, A. Lamouri, C. Redeuilh, K. Chen, C.-Z. Dong, S. Nowak, S. Ammar, C. Mangeney (2012), “Magnetic nanocrystals coated by molecularly imprinted polymers for the recognition of bisphenol A”, J Mater Chem., 22, 1807-1811.
7.Eggert, D.; Dash, P. K.; Serradji, N.; Dong, C. Z.; Clayette, P.; Heymans, F.; Dou, H.; Gorantla, S.; Gelbard, H. A.; Poluektova, L.; Gendelman, H. E. (2009) “Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders”, J Neuroimmunol., 213, 47-59.
8.Ezoulin, J. M.; Shao, B. Y.; Xia, Z.; Xie, Q.; Li, J.; Cui, Y. Y.; Wang, H.; Dong, C. Z.; Zhao, Y. X.; Massicot, F.; Qiu, Z. B.; Heymans, F.; Chen, H. Z. (2009) “Novel piperazine derivative PMS1339 exhibits tri-functional properties and cognitive improvement in mice”, Int J Neuropsychopharmacol., 12, 1409-19.
9.Touaibia, M.; Djimdé, A.; Cao, F.; Boilard, E.; Bezzine, S.; Lambeau, G.; Redeuilh, C.; Lamouri, A.; Massicot, F.; Chau, F.; Dong, C. Z.; Heymans, F. (2007) “ Inhibition of secreted phospholipase A2 (sPLA2). 4-Glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one (PMS1062) with broad activities ”, J. Med. Chem., 50, 1618-26.
10.Dong, C. Z.; Kumar, S.; Choi, W. T.; Madani, N.; Tian, S.; An, J.; Sodroski, J. G.; Huang Z. (2005) “Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand”, J. Med. Chem., 48, 7923-4.
11.Serradji, N.; Bensaid, O.; Martin, M.; Cisternino, S.; Rousselle, C.; Huet, J.; Redeuilh, C.; Lamouri, A.; Dong, C. Z.; Clayette, P.; Godfroid, J.-J.; Scherrmann, J.-M.; Dormont, D.; Heymans, F. (2004) “Structure-activity relationships in Platelet-Activating Factor. 12. Synthesis and biological evaluation of Platelet-Activating Factor antagonists with anti-HIV-1 activity”, J. Med. Chem., 47, 6410-9.
12.Dong, C. Z.; Romieu, A.; Mounier, C. M.; Heymans, F.; Roques, B. P.; Godfroid, J.-J. (2002) “Total direct chemical synthesis and biological activities of human group IIA secretory phospholipase A2”, Biochem. J., 365, 505-11. |
科研项目
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1.江汉大学交叉学科研究院多肽及蛋白质化学及其生物医学应用研究中心首席专家实验室建设和活动经费:2011-, 800万元, 在研, 主持.
2.广东工业大学特聘教授启动经费 : 2011-: 100万元, 在研, 主持.
3.Novartis, Development of peptide mimics of platelet glycoprotein VI as collagen tracer and antagonist, 2010-2013: 160 000 €,已结题,参与.
4.Université Paris Diderot, « Projets interdisciplinaires Paris Diderot 2011», Synthesis of 3-isoxazolidinone derivatives and their anti-bacteria activity against Chlamydia trachomatis, 2010-2011 : 25 000 €, 已结题,主持
5.Université Paris Diderot, « Projets interdisciplinaires Paris Diderot », Development of peptide mimics of platelet glycoprotein VI as collagen tracer and antagonist, 2009-2010: 25 000 €,已结题,参与
6.Paris Centre Université, new oxadiazolone derivatives with anti-inflammatory and anti-cytokine properties, 2008-2009: 10 000 €,已结题,主持
7.ARC, inhibitors of XIAP as new anticancer agents, 2007-2009: 50 000 €,已结题,主持
8.Laboratories SERVIER, inhibitors of XIAP as new anticancer agents, 2006-2007: 35 000 €,已结题,主持
9.BTG, Toxicity and pharmacokinetic study of PMS 601, a dual anti-PAF and anti-HIV compound, 2001,2 百万法郎,已结题,参与
10.Action Concertée Interdisciplinaire, Inhibitors of PLA2 and treatment of inflammation, 2000-2002,8 百万法郎,已结题,参与
11.YANIKEM s.a., Inhibitors of PLA2 and treatment of inflammation, 1998-2002,5 百万法郎,已结题,参与 |